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An Explanation Of The Term Asthma Pathophysiology

Pathophysiology is the study of what is abnormal, or what causes normal physiological processes to be disturbed. Asthma is a chronic inflammatory problem of the lungs and bronchioles which is characterized by reversible bronchospasm that often result from an exaggerated response to a variety of stimuli. This is the pathophysiological response which the lungs take when assaulted by an allergen.

What does all this mean? Well in the first place it means that asthma is not all in the mind and that it cannot be outgrown. It also means that it is a serious disease but is that you cannot catch it from someone else who has it. The pathophysiological changes resulted inflammation and symptoms such as coughing, wheezing and shortness of breath.

There are actually two types of asthma-extrinsic and intrinsic. An asthmatic who suffers from extrinsic asthma will have difficulty with allergic and immune responses. These individuals are often classified as being atopic, meaning that they have difficulty with IgE responses. Individuals who have asthmatic attacks from intrinsic factors means that they do not have an immune response but rather an allergic response to either aspirin or specific types of infections.

The more common of the two are those individuals who suffer from extrinsic asthma, or that which is immune mediated. In these cases the lungs of the individual becomes inflamed and the bronchial tubes become hyper responsive to allergens. The inflammation in the airway is an important part of the pathology and the underlying process which derives and maintains the inflammatory process.

The inflammation will activate the release of mast cells, eosinophils and macrophages in the airway. These substances increase the amount of mucus secretion present in the airways.

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